the term as used by sunstein seeks to bring together various traditions. however, there are significant differences between uses of the term in the cognitive and the social psychological research, and these differences are accompanied by very distinct evidential criteria. we suggest the term should refer to processes, which means that further evidence is required.

This rich collection will introduce students of philosophy and politics to the contemporary critical literature on the classical social contract political thinkers Thomas Hobbes , John Locke , and Jean-Jacques Rousseau . A dozen essays and book excerpts have been selected to guide students through the texts and to introduce them to current scholarly controversies surrounding the contractarian political theories of these three thinkers.

Peter Abelard (1079–1142 ce) was the most wide‐ranging philosopher of the twelfth century. He quickly established himself as a leading teacher of logic in and near Paris shortly after 1100. After his affair with Heloise, and his subsequent castration, Abelard became a monk, but he returned to teaching in the Paris schools until 1140, when his work was condemned by a Church Council at Sens. His logical writings were based around discussion of the “Old Logic”: Porphyry's Isagoge, aristotle'S Categories and (...) On Interpretation and boethius'S textbook on topical inference. They comprise a freestanding Dialectica (“Logic”; probably c.1116), a set of commentaries (known as the Logica [Ingredientibus], c. 1119) and a later (c. 1125) commentary on the Isagoge (Logica Nostrorum Petititoni Sociorum or Glossulae). In a work Abelard called his Theologia, issued in three main versions (between 1120 and c.1134), he attempted a logical analysis of trinitarian relations and explored the philosophical problems surrounding God's claims to omnipotence and omniscience. The Collationes (“Debates,” also known as “Dialogue between a Christian, a Philosopher and a Jew”; probably c.1130) present a rational investigation into the nature of the highest good, in which the Christian and the Philosopher (who seems to be modeled on a philosopher of pagan antiquity) are remarkably in agreement. The unfinished Scito teipsum (“Know thyself,” also known as the “Ethics”; c.1138) analyses moral action. (shrink)

Cas9/guide RNA (gRNA)‐based gene drive systems are expected to play a transformative role in malaria elimination efforts., whether through population modification, in which the drive system contains parasite‐refractory genes, or population suppression, in which the drive system induces a severe fitness load resulting in population decline or extinction. DNA sequence polymorphisms representing alternate alleles at gRNA target sites may confer a drive‐resistant phenotype in individuals carrying them. Modeling predicts that, for observed levels of SGV at potential target sites and observed (...) rates of de novo DRA formation, population modification strategies are uniquely resilient to DRAs. We conclude that gene drives can succeed when fitness costs incurred by drive‐carrying mosquitoes are low enough to prevent strong positive selection for DRAs produced de novo or as part of the SGV and that population modification strategies are less prone to failure due to drive resistance. (shrink)

This commentary argues against the indictment of current experimental practices such as piecemeal testing, and the proposed integrated experiment design (IED) approach, which we see as yet another attempt at automating scientific thinking. We identify a number of undesirable features of IED that lead us to believe that its broad application will hinder scientific progress.

This collection of essays is dedicated to the prolific career of Paul Ricoeur. Honoring his work, this anthology addresses questions and concerns that defined Ricoeur’s.

John Dewey looks to the Nicomachean Ethics of Aristotle for the general outlines of his ethical thought. In his 1932 Ethics, he describes the ethical framework that he shares with Aristotle in terms of knowledge, choice and character: "The formula was well stated by Aristotle. The doer of the moral deed must have a certain 'state of mind' in doing it. First, he must know what he is doing; secondly, he must choose it, and choose it for itself, and (...) thirdly, the act must be the expression of a formed and stable character."1 This paper examines the interaction of these elements within Aristotle's and Dewey's ethical thought. In particular, it discusses the idea of the good as a link between the character virtues and practical deliberation. It will show how this idea of the good that guides practical deliberation is also an expression of one's character virtues. (shrink)

Bringing between two covers the most influential and accessible articles on Plato's Republic, this collection illuminates what is widely held to be the most important work of Western philosophy and political theory. It will be valuable not only to philosophers, but to political theorists, historians, classicists, literary scholars, and interested general readers.

This paper draws on the social psychology of John Dewey to illustrate the importance of aporia, or confusion, to pragmatic pedagogywithin an ethics classroom. The strategic use of aporia solicits an appropriate expression of emotion within students. This emotional response involves dissatisfaction with the present; these dissatisfactions function as pragmatic ideals. Such ideals are not a refuge from the present, but enable students to critically and progressively reconstruct present experiences. Aporia is thus critically important for pedagogical success from a (...) pragmatist perspective. (shrink)

Huayan Buddhist philosophers and John Dewey share a perspective on emptiness or dependent origination. This article compares Dewey's local, contextual, and relational metaphysics with Huayan thinkers’ use of the metaphor of Indra's jewel net to extend their relational metaphysics to an infinite extent. Huayan thinkers base their ethics of compassion on the recognition of the infinite relatedness of all things. Dewey prefers constructing social institutions that foster experiences that are reliably aesthetically unified. This dispute is significant because pragmatism and (...) Buddhism both provide promising ethical positions based on the understanding of persons as temporally limited and relational. (shrink)

Generative AI programs can produce high-quality written and visual content that may be used for good or ill. We argue that a credit–blame asymmetry arises for assigning responsibility for these outputs and discuss urgent ethical and policy implications focused on large-scale language models.

J. Baird Callicott suggests in “The Land Aesthetic“ that the environmental community would be well served to focus on the aesthetic value of natural ecosystems as a source of intrinsic value in nature. But Callicott's own Humean and biological account of aesthetic value is inadequate as a basis for understanding the aesthetic appreciation of nature. This paper argues that John Dewey provides a holistic and transactional account of aesthetic value that is easily tailored to fit the ecocentric requirements of (...) a rich environmental aesthetics. (shrink)

DBS Think Tank IX was held on August 25–27, 2021 in Orlando FL with US based participants largely in person and overseas participants joining by video conferencing technology. The DBS Think Tank was founded in 2012 and provides an open platform where clinicians, engineers and researchers can freely discuss current and emerging deep brain stimulation technologies as well as the logistical and ethical issues facing the field. The consensus among the DBS Think Tank IX speakers was that DBS expanded in (...) its scope and has been applied to multiple brain disorders in an effort to modulate neural circuitry. After collectively sharing our experiences, it was estimated that globally more than 230,000 DBS devices have been implanted for neurological and neuropsychiatric disorders. As such, this year’s meeting was focused on advances in the following areas: neuromodulation in Europe, Asia and Australia; cutting-edge technologies, neuroethics, interventional psychiatry, adaptive DBS, neuromodulation for pain, network neuromodulation for epilepsy and neuromodulation for traumatic brain injury. (shrink)

Pancreatitis is a complex, progressively destructive inflammatory disorder. Alcohol was long thought to be the primary causative agent, but genetic contributions have been of interest since the discovery that rare PRSS1, CFTR and SPINK1 variants were associated with pancreatitis risk. We now report two associations at genome-wide significance identified and replicated at PRSS1-PRSS2 and X-linked CLDN2 through a two-stage genome-wide study. The PRSS1 variant likely affects disease susceptibility by altering expression of the primary trypsinogen gene. The CLDN2 risk allele is (...) associated with atypical localization of claudin-2 in pancreatic acinar cells. The homozygous CLDN2 genotype confers the greatest risk, and its alleles interact with alcohol consumption to amplify risk. These results could partially explain the high frequency of alcohol-related pancreatitis in men. © 2012 Nature America, Inc. All rights reserved. (shrink)

We report the identification of a recurrent, 520-kb 16p12.1 microdeletion associated with childhood developmental delay. The microdeletion was detected in 20 of 11,873 cases compared with 2 of 8,540 controls and replicated in a second series of 22 of 9,254 cases compared with 6 of 6,299 controls. Most deletions were inherited, with carrier parents likely to manifest neuropsychiatric phenotypes compared to non-carrier parents. Probands were more likely to carry an additional large copy-number variant when compared to matched controls. The clinical (...) features of individuals with two mutations were distinct from and/or more severe than those of individuals carrying only the co-occurring mutation. Our data support a two-hit model in which the 16p12.1 microdeletion both predisposes to neuropsychiatric phenotypes as a single event and exacerbates neurodevelopmental phenotypes in association with other large deletions or duplications. Analysis of other microdeletions with variable expressivity indicates that this two-hit model might be more generally applicable to neuropsychiatric disease. © 2010 Nature America, Inc. All rights reserved. (shrink)

In this first comprehensive treatment of Plato’s political thought in a long time, John Wallach offers a "critical historicist" interpretation of Plato. Wallach shows how Plato’s theory, while a radical critique of the conventional ethical and political practice of his own era, can be seen as having the potential for contributing to democratic discourse about ethics and politics today. The author argues that Plato articulates and "solves" his Socratic Problem in his various dialogues in different but potentially complementary ways. (...) The book effectively extracts Plato from the straightjacket of Platonism and from the interpretive perspectives of the past fifty years—principally those of Karl Popper, Leo Strauss, Hannah Arendt, M. I. Finley, Jacques Derrida, and Gregory Vlastos. The author’s distinctive approach for understanding Plato—and, he argues, for the history of political theory in general—can inform contemporary theorizing about democracy, opening pathways for criticizing democracy on behalf of virtue, justice, and democracy itself. (shrink)

"A person is not explainable in molecular, field-theoretical, or physiological terms alone." With that declaration, Nobel laureate Gerald M. Edelman goes straight to the heart of Nature's Imagination, a vibrant and important collection of essays by some of the world's foremost scientists. Ever since the Enlightenment, the authors write, science has pursued reductionism: the idea that the whole can be understood by examining and explaining each of its parts. But as this book shows, scientists in every discipline are reaching for (...) a new paradigm that accounts for the whole--from the individual person to the universe itself. Nature's Imagination gathers together the work of thirteen leading mathematicians, astronomers, neuroscientists, and philosophers, as they discuss the revolution sweeping the sciences. Here Roger Penrose, Oliver Sacks, John Barrow, Gregory Chaitin, Maragret Boden, and others explore how and why classic reductionism is falling by the wayside in their own fields. As Freeman Dyson writes in the introduction, science is an art form, not a philosophical method, and it is always in search of new tools. Reductionism has done its work, and scientists are in search of another. Roger Penrose offers a fascinating account of irreducibility in mathematics, starting with the example of an impossible triangle--a drawing of a triangular object twisted so that could not exist in three dimensions. He breaks the triangle into three parts, showing that each corner is physically possible; only in combination is the triangle impossible. Both Penrose and mathematician Gregory Chaitin explore Godel's incompleteness theorem--as does John Barrow, who explains that Chaitin's proof of the theorem shows that, if we ever arrive at a Theory of Everything, there may be a still deeper and simpler unifying theory beyond that. Other contributors discuss the changing thinking in neuroscience, and the limitations of a mechanical view of the mind: as Oliver Sacks writes, "if we are to have a model or theory of mind as this actually occurs in living creatures in the world, it may have to be radically different from anything like a computational one." In addition, this volume includes staunch defenders of the classic scientific approach, such as Peter Atkins ("The omnicompetence of science, and in particular the simplicity its reductionist insight reveals, should be accepted as a working hypothesis until, if ever, it is proved inadequate"). The advance of science has been so startlingly swift in the last century that it has begun to approach limits never dreamed of before. This remarkable volume captures the latest thinking on where we must turn if we are to truly understand oursevles and the universe we live in. (shrink)

A. Kenny, Frege, an introduction to the founder of modern analytic philosophy. London:Penguin, 1995. viii-h223pp. £7.99 T. Willamson, Vagueness. London:Routledge, 1994. xiii-f-325 pp. £35.00 TOM BU...

Medical ethics changed dramatically in the past 30 years because physicians and humanists actively engaged each other in discussions that sometimes led to confrontation and controversy, but usually have improved the quality of medical decision-making. Before then medical ethics had been isolated for almost two centuries from the larger philosophical, social, and religious controversies of the time. There was, however, an earlier period where leaders in medicine and in the humanities worked closely together and both fields were richer for it. (...) This volume begins with the 18th century Scottish Enlightenment when professors of medicine such as John Gregory, Edward Percival, and the American, Benjamin Rush, were close friends of philosophers like David Hume, Adam Smith, and Thomas Reid. They continually exchanged views on matters of ethics with each other in print, at meetings of elite intellectual groups, and at the dinner table. Then something happened, physicians and humanists quit talking with each other. In searching for the causes of the collapse, this book identifies shifts in the social class of physicians, developments in medical science, and changes in the patterns of medical education. Only in the past three decades has the dialogue resumed as physicians turned to humanists for help just when humanists wanted their work to be relevant to real-life social problems. Again, the book asks why, finding answers in the shift from acute to chronic disease as the dominant pattern of illness, the social rights revolution of the 1960's, and the increasing dissonance between physician ethics and ethics outside medicine. The book tells the critical story of how the breakdown in communication between physicians and humanists occurred and how it was repaired when new developments in medicine together with a social revolution forced the leaders of these two fields to resume their dialogue. (shrink)

Matoesian uses the 1991 rape trial of William Kennedy Smith to provide an in-depth analysis of language use and its role in that specific trial as well as the law in general. Examining both defense and prosecutorial linguistic strategies, he shows how language practices shape--and are shaped by--culture and the law.

In the United States, food banks served an estimated 46 million people in 2015. A combination of government policy reforms and political economic trends contributed to the rising numbers of individuals relying on private food assistance in the US, the United Kingdom and other high-income countries. Although researchers frequently map urban food environments, this project is one of the first to map private food assistance and potential need at the census-tract scale. We utilize Geographic Information Systems, demographic data, and food (...) assistance locations to develop a rapid assessment tool that could support food banks, pantries, soup kitchens, and government agencies that seek to answer the question of whether people with the greatest need have food distribution sites in close proximity. We define access based on distance and then calculate potential food insecurity using either poverty rates or a food insecurity index. We apply these methods in a case study analysis of Santa Clara County, California. Our findings suggest that food assistance distribution locations match the areas of potential need in more than 80% of urban census tracts. However, there are several potentially underserved locations and populations that could benefit from new food assistance operations. The poverty and index-based approaches show significant spatial overlap in mapped areas of high food insecurity and low access. The poverty only approach produces a higher estimate of food insecurity rates, is easier to calculate, and draws attention to the need to address poverty as a root cause of hunger. (shrink)

Introduction: -/- It is likely that Boethius (480-524ce) inaugurates, in Latin Christian theology, the consideration of personhood as such. In the Treatise Against Eutyches and Nestorius Boethius gives a well-known definition of personhood according to genus and difference(s): a person is an individual substance of a rational nature. Personhood is predicated only of individual rational substances. This chapter situates Boethius in relation to significant Christian theologians before and after him, and the way in which his definition of personhood is a (...) particular answer to the question, “Jesus has two natures, a divine nature and a human nature, but is one what?” Among Greek (and Syriac) speaking theologians, the typical answer is that Jesus is one ‘hypostasis’. Among Latin speaking theologians, the typical answer is that Jesus is one ‘persona’. It is Boethius’s definition of ‘persona’ that inaugurates personhood as such in Latin speaking theology. Although the Greek and Syriac theologians that I survey come close to a concept of personhood as a distinct category, they do not have such a concept and did not need it for their theological purposes. I show that Rusticus the Deacon is an early witness to this Latin theological invention, and also show that for later Latin theologians, the rationality condition for personhood does very little metaphysical work for their Trinitarian theology or Christology. -/- Further, this chapter surveys Patristic and Medieval Christian theologians’ answers to the question, “God the Father, God the Son, and God the Holy Spirit are one God, but each is one what?” The same replies as above are typically given by Christian theologians. These two theological questions frame the discussion about personhood (and ‘hypostasis’) and put a boundary around what a satisfying account of personhood (and ‘hypostasis’) would be. -/- In contemporary philosophy, there is a lot of attention paid to the rationality condition for personhood. But if we look at the text in which Boethius defines a person, we do not find any precise criteria for it. In other texts, he says that a rational being is one compatible with (capable of) thought and free choice of the will. What we find is that detailed discussion of personhood shows up in theological questions about the Trinity and Incarnation, but not in e.g., applied ethics. The intrusion of personhood into contemporary applied ethics with a focus on detailed and disputed criteria for rationality as a condition for personhood seems to be a modern development. From a Patristic and Medieval Christian theology point of view, trying to find just the right detailed criteria for rationality in order to define personhood is a wild goose chase. This chapter makes clear another contribution that Christian theology had for personhood. Given the theological issues at play in developing a notion of personhood, Christian theologians came to posit that e.g., an individual human is a person contingently (i.e. not essentially), but God the Father, God the Son, and God the Holy Spirit are each a person essentially. The contingency for created persons is not based on whether e.g., an individual human has conscious acts (as might be the case for John Locke) but on the possibility of a divine person’s assuming e.g., an individual human nature. -/- This sampling of Christian intellectual history spans over one thousand years. I make no claim of being exhaustive. The chapter consists of six sections, where each section covers significant historical conversation partners who together represent the sorts of things that Patristic and Medieval Christian theologians where concerned with in theorizing about ‘persona’ or ‘hypostasis’. -/- 1. Origen of Alexandria and the Cappadocians: Basil of Caesarea and Gregory of Nyssa 2. Miaphysites: Severus of Antioch, John Philoponus, and Peter of Callinicum 3. Boethius and Rusticus the Deacon: Rationality, Subsistence, and the Invention of Personhood 4. Neo-Chalcedonians (II): Leontius of Byzantium 5. Scholastic Neo-Chalcedonians (I): Gilbert of Poitiers, Richard of St. Victor, William of Auxerre, Alexander of Hales, Bonaventure, Thomas Aquinas, and William of Ware 6. Scholastic Neo-Chalcedonians (II): Henry of Ghent, John Duns Scotus, and William of Ockham . (shrink)